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别名
CXCL2,C-X-C motif chemokine 2,Growth-regulated protein beta,Gro-beta,Macrophage inflammatory protein 2-alpha,MIP2-alpha,GRO2,GROB,MIP2A,SCYB2,rHuGRO-β/CXCL2,HSF物种
HumanAccession
P19875表达序列
Ala35-Asn107表达宿主
E.coli分子量
9kDa (Reducing)
纯度
＞95% by SDS-PAGE内毒素含量
<0.1EU/μg活性
< 0.1 ng/ml标记
Unconjugated标签
No Tag性状
Lyophilized Powder缓冲体系
20mM Tris, 300mM NaCl, pH8.0溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.文献引用
1. Laila A Al-Alwan, Ying Chang (2013) J Immunol. 191(5):2731-41. 2. Louis M Pelus 1, Seiji Fukuda (2006) Exp Hemato. 34(8):1010-20.
Chemokines are small proteins (8–10 kDa) which direct the movement of leukocytes, including hematopoietic stem and progenitor cells, and can mobilize hematopoietic cells from marrow to peripheral blood where they can be used for transplantation，specialized in attracting inflammatory and structural cells to the sites of injury. GROs belong to the CXC family of chemokines bearing motif, glutamic acid, leucine, and arginine (R). In addition to GROs, this family also comprises epithelium-derived neutrophil activating peptide 78 (CXCL5), granulocyte chemotactic protein 2 (CXCL6), neutrophil-activating peptide 2 (CXCL7), and IL-8 (CXCL8). CXCL1, CXCL2, and CXCL3 are well known as powerful neutrophil chemoattractants and are involved in cancer metastasis, angiogenesis, and wound healing. Recently, GROs have been postulated to play a role in asthma severity and asthmatic airway remodeling.
电泳JSON
2μg (R: reducing condition, N: non-reducing condition).
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