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Rabbit抗原名称
ANTITHROMBIN III分子别名
ATIII免疫原
Recombinant ProteinAccession
P01008克隆号
SDT-294-303抗体类型
Rabbit mAb应用
Sandwich ELISA反应种属 ?
Hu交叉反应
Does not recognize thrombin, PIC complex, tPA-PAI-1 complex纯化方式
Protein A浓度
2 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.
| 应用 | 稀释度 |
|---|---|
| Sandwich ELISA | N/A |
Antithrombin III (ATIII) is a nonvitamin K-dependent protease that inhibits coagulation by neutralizing the enzymatic activity of thrombin (factors IIa, IXa, Xa). Antithrombin III activity is markedly potentiated by heparin, the principal mechanism by which both heparin and low–molecular-weight heparin result in anticoagulation. Thrombin–antithrombin complex (TAT) is a protein complex of thrombin and antithrombin. It is a marker of net activation of coagulation. TAT is formed in response to the high thrombin level caused by coagulation following a ruptured vessel. Since thrombin is rapidly bound by antithrombin, TAT is a useful measure for thrombin level in the blood. Thrombin can pass the blood–brain barrier, destroying neurons and potentially causing cerebral edemas. The half-life of TAT is approximately 15 minutes.
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