Antithrombin III Recombinant Rabbit mAb (SDT-294-303)

Product Introduction

• Host

  Rabbit

• Antigen

  Antithrombin III

• Synonyms

  ATIII

• Immunogen

  Recombinant Protein

• Accession

  P01008

• Clone Number

  SDT-294-303

• Antibody Type

  Rabbit mAb

• Application

  Sandwich ELISA

• Reactivity

  Hu

• Purification

  Protein A

• Concentration

  2 mg/ml

• Conjugation

  Unconjugated

• Physical Appearance

  Liquid

• Storage Buffer

  PBS pH7.4, 0.03% Proclin 300

• Stability & Storage

  12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

• • Sandwich ELISA

    N/A

• Antithrombin III (ATIII) is a nonvitamin K-dependent protease that inhibits coagulation by neutralizing the enzymatic activity of thrombin (factors IIa, IXa, Xa). Antithrombin III activity is markedly potentiated by heparin, the principal mechanism by which both heparin and low–molecular-weight heparin result in anticoagulation. Thrombin–antithrombin complex (TAT) is a protein complex of thrombin and antithrombin. It is a marker of net activation of coagulation. TAT is formed in response to the high thrombin level caused by coagulation following a ruptured vessel. Since thrombin is rapidly bound by antithrombin, TAT is a useful measure for thrombin level in the blood. Thrombin can pass the blood–brain barrier, destroying neurons and potentially causing cerebral edemas. The half-life of TAT is approximately 15 minutes.

• Paired Recommendations

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