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Rabbit抗原名称
Succinyllysine分子别名
Ksucc, 琥珀酰化免疫原
Synthetic Peptide抗体类型
Recombinant mAb Mix抗体同种型
IgG纯化方式
Protein A浓度
1 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, -20 °C as supplied
应用
WB
稀释度
应用 稀释度 推荐种属 Dot Blot 1:1000 WB 1:500 Ms
Succinyllysine is a form of post-translational modification (PTM) involving the attachment of a succinyl group to the lysine residues in proteins. This modification, which is reversible and dynamic, has been identified in both prokaryotic and eukaryotic cells and is involved in the regulation of various cellular and biological processes. Succinyllysine is implicated in altering enzyme activities of metabolic enzymes and controlling protein-protein or protein-nucleic acid interactions, which can have significant effects on cellular functions such as replication, transcription, and are associated with various diseases including cardiovascular diseases and cancer. The modification is suggested to be regulated by enzymes like sirtuins and is responsive to different physiological conditions, indicating its importance in cellular metabolism and disease development.
免疫印迹
WB result of S-RMabMix™ Succinyllysine Rabbit mAb
Primary antibody: S-RMabMix™ Succinyllysine Rabbit mAb at 1/500 dilution
Lane 1: mouse liver lysate 20 µg
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: Multiple
Observed MW: Multiple
斑点杂交
Dot blot result of S-RMabMix™ Succinyllysine Rabbit mAb
Lane 1: Modified peptide library (Succinyl lysine)
Lane 2: Unmodified peptide library control
Lane 3: Modified peptide library (Itaconyl lysine)
Lane 4: Modified peptide library (Malonyl lysine)
Lane 5: Modified peptide library (Fumaryl lysine)
Lane 6: Modified peptide library (Crotonyl lysine)
Lane 7: Modified peptide library (Butyryl lysine)
Lane 8: Modified peptide library (L-lactyl lysine)
Lane 9: Modified peptide library (Propionyl lysine)
Lane 10: Modified peptide library (Actyl lysine)
Primary antibody: S-RMabMix™ Succinyllysine Rabbit mAb at 1/1000 dilution
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution

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