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产品中心 抗体 蛋白翻译后修饰(PTM)抗体

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S-RMabMix™ L-Lactyl Lysine Rabbit mAb STAR

L-Kla,Kla‌,L‑乳酸化,L-乳酰化

价格 ￥1,300.00 （ 供应商现货 ： 3-5个工作日）
货号 S0B0719
规格
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产品介绍

产品介绍 引用文献(1) 评论(0)

产品规格

  • 宿主来源

    Rabbit

  • 分子别名

    L-Kla, Kla‌, L‑乳酸化，L-乳酰化

  • 抗体类型

    Recombinant mAb Mix

  • 抗体同种型

    IgG

  • 纯化方式

    Protein A

  • 浓度

    1 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, -20°C as supplied

  • 应用

    ICC ?

    WB

    IP

  • 稀释度

    应用 稀释度
    Dot Blot 1:1000
    WB 1:1000
    IP 1:50
    ICC 1:500
背景介绍

  • Lysine lactylation is an emerging post-translational modification that occurs in cellular metabolism, specifically referring to the accumulation of lactic acid modifying lysine residues on histones. Lysine lactylation modifies the chromatin structure, thereby affecting gene expression. Research has found that lactylation sites are widely distributed in gene promoter regions, closely associated with gene transcriptional activation. Lysine lactylation also participates in energy metabolism processes, potentially related to the dynamic balance regulation of histone lysine acetylation.

  • 免疫印迹

    • WB result of S-RMabMix™ L-Lactyl Lysine Rabbit mAb
      Primary antibody: S-RMabMix™ L-Lactyl Lysine Rabbit mAb at 1/1000 dilution
      Lane 1: untreated HeLa whole cell lysate 20 µg
      Lane 2: HeLa treated with 100 mM Lactate sodium for 24 hours whole cell lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: Multiple
      Observed MW: Multiple

  • 斑点杂交

    • Dot blot result of S-RMabMix™ L-Lactyl Lysine Rabbit mAb
      Lane 1: Modified peptide library (L-lactyl lysine)
      Lane 2: Unmodified peptide library control
      Lane 3: Modified peptide library (D-lactyl lysine)
      Lane 4: Modified peptide library (β-hydroxybutyryl lysine)
      Lane 5: Modified peptide library (Fumaryl lysine)
      Lane 6: Modified peptide library (Crotonyl lysine)
      Lane 7: Modified peptide library (Succinyl lysine)
      Lane 8: Modified peptide library (Butyryl lysine)
      Lane 9: Modified peptide library (Propionyl lysine)
      Lane 10: Modified peptide library (Actyl lysine)
      Primary antibody: S-RMabMix™ L-Lactyl Lysine Rabbit mAb at 1/1000 dilution
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution

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