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产品规格
宿主来源
Human抗原名称
PD-1抗体类型
Recombinant mAb抗体同种型
IgG4,k应用
Blocking of PD-1/PD-L1 signaling Functional assays反应种属 ?
Hu纯化方式
Protein A浓度
5 mg/ml标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, containing no preservative. Endotoxin level is ≤ 1 EU/mg储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
文献引用
背景介绍
Pembrolizumab is a humanized monoclonal IgG4 kappa antibody directed against human cell surface PD-1 (programmed death receptor-1) on lymphocytes. The PD-1 receptor provides an important “immune checkpoint,” which helps prevent the immune system from attacking itself.
验证数据
![item.picture[0].fileOrgName](https://univ-pmc.oss-cn-shanghai.aliyuncs.com/product.imager.attribute/0/ad6779f9-572b-466f-a793-17065168c4e1.jpg)
Pembrolizumab (anti-PD-1), dilutions start from 1 μg/ml) can bind to Immobilized recombinant Human PD-1 his tag (UA010004 form UA.BIO) at 0.5 μg/ml (50 μl/well) as coating antigen.
EC50=13.74 ng/ml
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