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宿主来源
Syrian Hamster抗原名称
CD28免疫原
C57BL/6 mouse T cell lymphoma EL-4 cells克隆号
37.51抗体类型
Syrian hamster mAb抗体同种型
Syrian Hamster IgG2应用
in vitro T cell stimulation/activation, in vivo CD28 blockade反应种属 ?
Ms纯化方式
Protein G浓度
Lot specific* (generally 4 to 11 mg/ml)*分子量
150 kDa
纯度
>95%(Determined by SDS-PAGE)内毒素含量
<2EU/mg (<0.002EU/μg), 0.2 μM filtered Determined by LAL gel clotting assay标记
Unconjugated性状
Liquid缓冲体系
PBS pH6.0 containing no preservative储存条件
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
This antibody recognizes the same epitope as clone 37.51.
This monoclonal antibody reacts with mouse CD28, a 45 kDa costimulatory receptor and a member of the lg superfamily, CD28 is expressed by thymocytes, most peripheral T cells, and NK cells. CD28 is a receptor for CD80 (B7-1) and CD86 (B7-2). Signaling through CD28 augments lL-2 and IL-2 receptor expression as well as cytotoxicity of CD3-activated T cells. This antibody has been shown to stimulate the proliferation and cytokine production by activated T and NK cells and provide a costimulatory signal for CTL induction.
引用文献(1)
- A novel FTO-targeting nanodrug induces disulfidptosis and ameliorates the suppressive tumor immune environment to treat uveal melanoma
Hao Tian; Hongpei Deng; Xinlong Liu; Chang Liu; Chuan Zhang; Kam W. Leong; Jing Ruan; Xianqun Fan
Biomaterials. 2025 Feb 12 ; 0142-9612
影响因子： 12.8
货号：S0B0003E产品名称：NA/LE Syrian Hamster anti-mouse CD28 mAb
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